![]() Do not use your own autoinjectors on a casualty. Use the casualty's own ATNAAs when providing aid. If self-aid (one ATNAA injection) has been administered, administer in rapid succession two (2) additional ATNAA injections into the casualty's lateral thigh muscle or buttocks.If you encounter a service member suffering from any of the severe symptoms of organophosphorus nerve agent poisoning, render the following aid: A buddy must administer the second and third injections, if needed. If symptoms of organophosphorus nerve agent poisoning are not relieved after administering one injection, seek someone else to check your symptoms.Giving yourself a second set of injections may cause an overdose of the ATNAA which could result in incapacitation. If you are able to ambulate, know who you are, and where you are, you will NOT need a second injection. Wait 10 to 15 minutes for the antidote to take effect.Push ejected needle through a pocket flap (or other thick and conspicuous part of outer clothing). Using a hard surface, bend needle into hook.Place front end on outer thigh and push hard until injector functions.Administer one (1) ATNAA into your lateral thigh muscle or buttocks as follows:.The following instructions should be given to service members for the administration of ATNAA single-dose injections. Severe muscular twitching and general weakness.Increased wheezing and increased difficulty in breathing.Localized sweating and muscular twitching in the area of contaminated skin.Tightness of chest or difficulty in breathing.Difficulty in seeing (dimness of vision and miosis).Common Symptoms of Organophosphorus Nerve Agent Exposure Mild Symptoms If a service member is encountered suffering from severe signs of organophosphorus nerve agent poisoning and ATNAA self-aid has not been administered, immediately administer in rapid succession three (3) ATNAA injections into the casualty's lateral thigh muscle or buttocks. ![]() Another service member must administer the second and third injections.Īdditional Doses: If you encounter a service member suffering from severe symptoms of organophosphorus nerve agent poisoning listed in Table 1 and one ATNAA has been self-administered, administer two (2) additional ATNAA injections intramuscularly in rapid succession into the casualty's lateral thigh muscle or buttocks.Ĭasualties with severe symptoms may experience most or all of the mild symptoms of organophosphorus nerve agent poisoning, plus most or all of the severe symptoms listed in Table 1. If, after 10 to 15 minutes, the symptoms of organophosphorus nerve agent poisoning are not relieved, seek someone else to check your symptoms. Wait 10 to 15 minutes for ATNAA to take effect. įirst Dose: If you experience some or all of the mild symptoms of nerve agent exposure listed in Table 1, self-administer one (1) ATNAA injection intramuscularly into the lateral thigh muscle or buttocks. Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit.Close supervision of all treated service members is indicated for at least 48 to 72 hours.The ATNAA autoinjector is intended as an initial treatment of the symptoms of organophosphorus nerve agent poisoning as soon as symptoms appear definitive medical care should be sought immediately. Only administer ATNAA to service members experiencing symptoms of organophosphorus nerve agent poisoning in a situation where exposure is known or suspected.ATNAA should be self- or buddy–administered by service members after donning protective mask and hood at the first sign of a chemical attack, and only if some or all of the mild symptoms of organophosphorus nerve agent exposure are present.For optimal reactivation of organophosphorus-inhibited cholinesterase, the ATNAA should be administered as soon as possible after appearance of symptoms of organophosphorus nerve agent poisoning.Note that individuals may not have all symptoms included under the mild or severe symptom category. Three (3) ATNAA single-dose autoinjectors should be available for use by each service member at risk for organophosphorus nerve agent poisoning one (1) for mild symptoms plus two (2) more for severe symptoms.Atropine and Pralidoxime Dosage and Administration Important Administration Information Expand Indications and Usage for Atropine and PralidoximeĪTNAA is indicated for the treatment of poisoning by susceptible organophosphorus nerve agents having anticholinesterase activity in adults.
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